Aquaporins at a glance.

نویسنده

Alan S Verkman

چکیده

With a concentration of 55,000 mM, water is by far the most prevalent molecule in biological systems. For many years it was assumed that biological membranes are freely water permeable, so that the existence of a family of water channels would not have been predicted. However, biophysical studies in erythrocytes and kidney tubules in the 1960s through the 1980s revealed that some membranes are more water permeable than others and have certain biophysical properties, such as weakly temperature-dependent water transport and an

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